Thank you. I just waded through the Deplatform Disease post that was quite extensive on the vaccines and the data. Phew! He did sort of make a dig at the Novavax “fandom” as he calls it. I was able to distill that…. We have far more data for mRNA vaccines, the safety is excellent, and there lingers the question of myocarditis (mostly you…
Thank you. I just waded through the Deplatform Disease post that was quite extensive on the vaccines and the data. Phew! He did sort of make a dig at the Novavax “fandom” as he calls it. I was able to distill that…. We have far more data for mRNA vaccines, the safety is excellent, and there lingers the question of myocarditis (mostly young males) in also the Novavax but due to the power not clear.
I will say that in this big wave, I may get the sense of a slight uptick in interest in the updated booster. Whether that translates into actually taking your child to get it, I think still low. Most of my patients were vaccinated last in 2021-2022. And it doesn’t even dawn on people to test when they are sick. So we shall see.
As for Novavax, Vincent Racaniello and Daniel Griffin (Clinical Updates on This Week in Virology) and (if I recall aright) Michael Osterholm seem to be "fans" (what a weird way to denigrate something), i.e. looking forward to the protein-based vaccine. There are proven fewer side effects and the question of lengthier durability (to be assessed). Also it should prove more attractive to those who distrust the mRNA vaccines.
I waded through the post as well, and as a lawyer (could never do the hardest math and science) who is knocked out by mRNA, I am now confused about how much “worse” Novavax is and anxious about the whole thing. I’ll get Novavax again this year, like last year, and am still a novid, but dang this isn’t easy and living with all this access to information frequently doesn’t make it easier.
Right, but as he noted, it’s a great alternative and does all the things we need. My impression was that he was intending to provide data that didn’t support the “fandom” per se. Not that it wasn’t a good vaccine, particularly for those w post vaccine symptoms at the end of the range.
I encourage you to take a look at the data wonk analysis LOL. It’s extensive but he also distills it (with the benefit of seeing the data in his article not just footnotes). It’s but one person’s perspective and certainly his assessment of all the data.
It is indeed a great alternative to the mRNA vaccines. But even my medical assistant who still believes there are microchips in it (omg) and got 2 doses of J&J only, is not interested in ANY further vaccine for Covid. So I am unsure ultimately what niche (other than the less intense post vaccine side effects) it will fill. He seems to feel the data supports a partially less optimal response, seen at a minimum at the CD8 response level.
But as always, any vaccine has been shown better than none. And amazingly still better than infection at generating immunity.
Your medical assistant believes there are microchips in a vaccine?!! Good grief, she has indeed drunken the lemonade. Hopefully she’ll not get covid 🙏🏼
I really have an issue with the obsession with “which vaccine is the best”. An analogy I would use is I get asked what camera I used for my wildlife photography. I said all cameras are good, it’s the photographer (and sometimes plain dumb luck) that make for a great photo. The real questions should be, ‘did you die’, ‘did you go to the hospital/ICU’. In other words, prevented progression to severe disease. Seems we forget that our upper airways are constantly being assaulted by antigens. We are constantly infected and hopefully our mucosal immunity stops the progression from SARS-CoV-2 to COVID-19.
Thank you. I just waded through the Deplatform Disease post that was quite extensive on the vaccines and the data. Phew! He did sort of make a dig at the Novavax “fandom” as he calls it. I was able to distill that…. We have far more data for mRNA vaccines, the safety is excellent, and there lingers the question of myocarditis (mostly young males) in also the Novavax but due to the power not clear.
I will say that in this big wave, I may get the sense of a slight uptick in interest in the updated booster. Whether that translates into actually taking your child to get it, I think still low. Most of my patients were vaccinated last in 2021-2022. And it doesn’t even dawn on people to test when they are sick. So we shall see.
As for Novavax, Vincent Racaniello and Daniel Griffin (Clinical Updates on This Week in Virology) and (if I recall aright) Michael Osterholm seem to be "fans" (what a weird way to denigrate something), i.e. looking forward to the protein-based vaccine. There are proven fewer side effects and the question of lengthier durability (to be assessed). Also it should prove more attractive to those who distrust the mRNA vaccines.
I waded through the post as well, and as a lawyer (could never do the hardest math and science) who is knocked out by mRNA, I am now confused about how much “worse” Novavax is and anxious about the whole thing. I’ll get Novavax again this year, like last year, and am still a novid, but dang this isn’t easy and living with all this access to information frequently doesn’t make it easier.
Right, but as he noted, it’s a great alternative and does all the things we need. My impression was that he was intending to provide data that didn’t support the “fandom” per se. Not that it wasn’t a good vaccine, particularly for those w post vaccine symptoms at the end of the range.
Happy to have an alternative to mRNA vaccines as for some people the reaction (presumably to nanoparticles) can be severe.
I encourage you to take a look at the data wonk analysis LOL. It’s extensive but he also distills it (with the benefit of seeing the data in his article not just footnotes). It’s but one person’s perspective and certainly his assessment of all the data.
It is indeed a great alternative to the mRNA vaccines. But even my medical assistant who still believes there are microchips in it (omg) and got 2 doses of J&J only, is not interested in ANY further vaccine for Covid. So I am unsure ultimately what niche (other than the less intense post vaccine side effects) it will fill. He seems to feel the data supports a partially less optimal response, seen at a minimum at the CD8 response level.
But as always, any vaccine has been shown better than none. And amazingly still better than infection at generating immunity.
Your medical assistant believes there are microchips in a vaccine?!! Good grief, she has indeed drunken the lemonade. Hopefully she’ll not get covid 🙏🏼
LOL, yeah. Like her constant cell phone use isn’t tracking her. Good grief.
This is a comment I made on a note.
I really have an issue with the obsession with “which vaccine is the best”. An analogy I would use is I get asked what camera I used for my wildlife photography. I said all cameras are good, it’s the photographer (and sometimes plain dumb luck) that make for a great photo. The real questions should be, ‘did you die’, ‘did you go to the hospital/ICU’. In other words, prevented progression to severe disease. Seems we forget that our upper airways are constantly being assaulted by antigens. We are constantly infected and hopefully our mucosal immunity stops the progression from SARS-CoV-2 to COVID-19.
Went to the Deplatform Disease website (never heard of it before, what's it's pov?) and couldn't find the post you're referring too.
https://open.substack.com/pub/deplatformdisease/p/novavax-has-a-good-covid-19-vaccine?r=g9lpt&utm_medium=ios
Thanks