I’m overweight and work in healthcare so I meet criteria for booster. I had Pfizer. I’m so torn on booster! Do I choose Moderna? Half dose vs full dose? They are both mRNA? I would really love your educated opinion. I realize any booster is a good thing!
I’m overweight and work in healthcare so I meet criteria for booster. I had Pfizer. I’m so torn on booster! Do I choose Moderna? Half dose vs full dose? They are both mRNA? I would really love your educated opinion. I realize any booster is a good thing!
Indications are that a boost with the sub-dose Moderna will still enhance your immunity. They ARE both mRNA, and they use similar elements of the various virus (especially spike) protein domains; both use the receptor binding domain (RBD) as a major element of their structures, but there are also subtle differences.
What you don't mention is, have you been infected? Those with prior infection with COVID-19 AND subsequent vaccination have a much higher level of humeral response. You also don't mention your age; immunogenicity (effectiveness) decreases generally with age.
In my mind, there's little doubt you would benefit from a booster. Either will work. You can really take the simple route: Whatever you can get first.
I’m overweight and work in healthcare so I meet criteria for booster. I had Pfizer. I’m so torn on booster! Do I choose Moderna? Half dose vs full dose? They are both mRNA? I would really love your educated opinion. I realize any booster is a good thing!
Indications are that a boost with the sub-dose Moderna will still enhance your immunity. They ARE both mRNA, and they use similar elements of the various virus (especially spike) protein domains; both use the receptor binding domain (RBD) as a major element of their structures, but there are also subtle differences.
What you don't mention is, have you been infected? Those with prior infection with COVID-19 AND subsequent vaccination have a much higher level of humeral response. You also don't mention your age; immunogenicity (effectiveness) decreases generally with age.
In my mind, there's little doubt you would benefit from a booster. Either will work. You can really take the simple route: Whatever you can get first.