Ivermectin had shown some minor anti-viral potential in-silico in extremely large doses. If it were used in sufficient dose to have a similar effect in humans, as an "antiviral" its adverse effect on the central nervous system would have been more widely reported. Note that the Veterans Administration discontinued a large ivermectin and …
Ivermectin had shown some minor anti-viral potential in-silico in extremely large doses. If it were used in sufficient dose to have a similar effect in humans, as an "antiviral" its adverse effect on the central nervous system would have been more widely reported. Note that the Veterans Administration discontinued a large ivermectin and hydroxychloroquine study due to futility and adverse mortality outcomes.
For parasites, the effective dose is much smaller because its CNS effect on parasites requires a lower concentration, due to their relative size. Its antiviral effect was never actually proven in-silico, but that identification was made by a rather simplistic AI analysis of thousands of existing compounds early in the outbreak.
Ivermectin had shown some minor anti-viral potential in-silico in extremely large doses. If it were used in sufficient dose to have a similar effect in humans, as an "antiviral" its adverse effect on the central nervous system would have been more widely reported. Note that the Veterans Administration discontinued a large ivermectin and hydroxychloroquine study due to futility and adverse mortality outcomes.
For parasites, the effective dose is much smaller because its CNS effect on parasites requires a lower concentration, due to their relative size. Its antiviral effect was never actually proven in-silico, but that identification was made by a rather simplistic AI analysis of thousands of existing compounds early in the outbreak.