Vaccine Table Update: Lots on Delta

You know the drill. Additions since last iteration are in peach. Data sources (and explanations) are below.

Pfizer

  • A Lancet study (blood from 250 people) found Delta reduced neutralization antibodies by 5.8-fold

  • A study in the UK (1,054 people with Delta) found 87.9% efficacy 2 weeks after the second dose. Efficacy after one dose was 33.2%.

  • An analysis (14,019 people with Delta) found 94% efficacy against severe disease (i.e. admission to hospital) after one dose and 96% efficacy after two doses.

  • In a Scottish study (7,723 people with Delta) 134 people were hospitalized. Vaccine had 79% efficacy.

  • If you missed it, here is the myocarditis update

Moderna

  • Delta: No updates since the last iteration, but just because everyone always asks… I have no reason to believe that Moderna would be different than Pfizer

  • If you missed it, here is the myocarditis update

AstraZeneca (AZ)

  • A study in the UK (1,054 people with Delta) found 59.8% efficacy 2 weeks after the second dose. Efficacy after one dose was 32.9%.

  • An analysis (14,019 people with Delta) found 71% efficacy against severe disease (i.e. admission to hospital) after one dose and 92% efficacy after two doses.

  • A Scottish Lancet study (7,723 people with Delta) found 60% efficacy

  • Booster trial for Beta variant vaccine has started (here)

Johnson & Johnson (J&J)

  • Working well against Beta and Gamma (both in terms of antibody and T-cell response; here)

  • J&J said it’s testing whether its vaccine works against Delta, but no data is available yet (I’m keeping my eye out). There are a lot of opinions circulating regarding whether J&J people need a second dose. I want to be clear that there has been no scientific evidence showing the need, safety, or effectiveness yet.

Novavax

  • If you missed the update from Phase III trials, go here

Mixing vaccines

  • Two studies on the mixing of AZ and Pfizer found safe and effective (here, here)

Natural Infection

  • Preliminary evidence is showing that natural immunity not working against Delta. But our confidence is low; we need more studies (here)

Love, YLE