Si quiere leer la versión en español, pulse aquí. One of the top concerns among young adults and parents is that COVID19 vaccines may negatively impact fertility. In fact, the latest Kaiser Family Foundation poll found 2 out of 3 (66%) parents are concerned the vaccine may affect their child’s future fertility.
I absolutely love your emails and so appreciate the time you take to share them. They are logical, fact based, and laymen friendly. I have shared them with so m any other people, whether they are on the same page as I am or not. You lay things out so well, those that may lean towards disinformation should have a hard time supporting their theories. Thank you so much for what you’re doing!
So incredibly helpful and "on target" vs the propaganda (with pseudo non real science "explanations") being circulated by the anti vaxx crowd. Unfortunately that crowd will either not encounter the data (or explanation) or will dismiss it "as a product of the mainstream health consensus, beholden to the pharma companies... produced by people afraid of bucking the consensus for (whatever reason)...."
Thank you for taking the time to bring this literature to those of us who don't study this literature rigorously. As you say, there area lots of people who are anxious about issues you addressed: effects on pregnancy and reproductive health. We can't fully answer questions about long term effects until the data emerge. And some people, needing answers where there are none, have a tendency to believe stories that sound convincing. That's why it is so important that you continue disseminating the data as it trickles in. In the end, facts will prevail.
It's a little ironic that, just as the high mortality rate of Covid-19 is largely due to people unwittingly transmitting it to others who then fall ill, just so the disinformation transmitted through these myths is impeding the acceptance of measures to mitigate the pandemic. It shows how vulnerable we all are to lack of knowledge.
I want to disagree with "There are only two possible ways a vaccine could impact fertility long-term". The unknown ways have a way of presenting themselves to the astonishment of those who said they weren't possible. The long term effects of thalidomide weren't known until the babies were born. The long term effects of the vaccines on the reproductive system of children receiving them will not be known for years.
Thank you for your explanation on the immune response. I hadn't gotten a concise explanation as to why we see effects within the first two months, generally. That makes so much sense, and I'll keep this post in my back pocket for explanation to others! Thanks so much for your work!
The menses study says that the ~15% of women who had two doses in one cycle had the biggest effect. ~10% of those women had a clinically significant change in the cycle length (8 days or more), which was ~2.5X more than the unvaccinated group.
So my question about the fertility study is, would it be able to detect an effect on fertility among women with clinically significant changes in their cycle length? The fraction of women who had two doses in one cycle and then had clinically significant changes in cycle length would be 10% * 15% = 1.5%. Since difference in fertility rates of 2% were not considered significant, I assume the answer is no, we do not have enough evidence to say whether or not getting two doses in one cycle affects fertility. Is that correct?
Hello. I am sorry, this is off topic but I do not know how else to message you. Would you please offer a discussion of a recent CDC report (link below) comparing the various types of immunity during the delta wave? In particular, how well (or not) do you think hybrid immunity might work in reverse (vaccination followed by infection)?
Also what is your take on this recent lead for a pan-cornavirus vaccine: targeting the transcription-replication complex of the virus rather than the spike protein?
I absolutely love your emails and so appreciate the time you take to share them. They are logical, fact based, and laymen friendly. I have shared them with so m any other people, whether they are on the same page as I am or not. You lay things out so well, those that may lean towards disinformation should have a hard time supporting their theories. Thank you so much for what you’re doing!
So incredibly helpful and "on target" vs the propaganda (with pseudo non real science "explanations") being circulated by the anti vaxx crowd. Unfortunately that crowd will either not encounter the data (or explanation) or will dismiss it "as a product of the mainstream health consensus, beholden to the pharma companies... produced by people afraid of bucking the consensus for (whatever reason)...."
Thank you for taking the time to bring this literature to those of us who don't study this literature rigorously. As you say, there area lots of people who are anxious about issues you addressed: effects on pregnancy and reproductive health. We can't fully answer questions about long term effects until the data emerge. And some people, needing answers where there are none, have a tendency to believe stories that sound convincing. That's why it is so important that you continue disseminating the data as it trickles in. In the end, facts will prevail.
It's a little ironic that, just as the high mortality rate of Covid-19 is largely due to people unwittingly transmitting it to others who then fall ill, just so the disinformation transmitted through these myths is impeding the acceptance of measures to mitigate the pandemic. It shows how vulnerable we all are to lack of knowledge.
I want to disagree with "There are only two possible ways a vaccine could impact fertility long-term". The unknown ways have a way of presenting themselves to the astonishment of those who said they weren't possible. The long term effects of thalidomide weren't known until the babies were born. The long term effects of the vaccines on the reproductive system of children receiving them will not be known for years.
Thank you for your explanation on the immune response. I hadn't gotten a concise explanation as to why we see effects within the first two months, generally. That makes so much sense, and I'll keep this post in my back pocket for explanation to others! Thanks so much for your work!
The menses study says that the ~15% of women who had two doses in one cycle had the biggest effect. ~10% of those women had a clinically significant change in the cycle length (8 days or more), which was ~2.5X more than the unvaccinated group.
So my question about the fertility study is, would it be able to detect an effect on fertility among women with clinically significant changes in their cycle length? The fraction of women who had two doses in one cycle and then had clinically significant changes in cycle length would be 10% * 15% = 1.5%. Since difference in fertility rates of 2% were not considered significant, I assume the answer is no, we do not have enough evidence to say whether or not getting two doses in one cycle affects fertility. Is that correct?
Awesome info!
Hello. I am sorry, this is off topic but I do not know how else to message you. Would you please offer a discussion of a recent CDC report (link below) comparing the various types of immunity during the delta wave? In particular, how well (or not) do you think hybrid immunity might work in reverse (vaccination followed by infection)?
https://www.reuters.com/business/healthcare-pharmaceuticals/prior-covid-infection-more-protective-than-vaccination-during-delta-surge-us-2022-01-19/
Also what is your take on this recent lead for a pan-cornavirus vaccine: targeting the transcription-replication complex of the virus rather than the spike protein?
https://www.nature.com/articles/d41586-021-03110-4